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diff --git a/sci-libs/htslib/htslib-1.0.ebuild b/sci-libs/htslib/htslib-1.0.ebuild
new file mode 100644
index 000000000000..f3ab7398967a
--- /dev/null
+++ b/sci-libs/htslib/htslib-1.0.ebuild
@@ -0,0 +1,45 @@
+# Copyright 1999-2015 Gentoo Foundation
+# Distributed under the terms of the GNU General Public License v2
+# $Id$
+
+EAPI=5
+
+inherit multilib toolchain-funcs
+
+DESCRIPTION="C library for high-throughput sequencing data formats"
+HOMEPAGE="http://www.htslib.org/"
+SRC_URI="mirror://sourceforge/samtools/${PV}/${P}.tar.bz2"
+
+SLOT="0"
+LICENSE="MIT"
+KEYWORDS="amd64 x86 ~amd64-linux ~x86-linux"
+IUSE="static-libs"
+
+src_prepare() {
+	sed \
+		-e "/libdir/s:lib$:$(get_libdir):g" \
+		-i Makefile || die
+}
+
+src_compile() {
+	emake \
+		AR="$(tc-getAR)" \
+		CC="$(tc-getCC)" \
+		CFLAGS="${CFLAGS}" \
+		LDFLAGS="${LDFLAGS}"
+}
+
+src_install() {
+	emake \
+		DESTDIR="${D}" \
+		prefix="${EPREFIX}/usr" \
+		install
+
+	rm "${ED}/usr/share/man/man1/libhts.so.1" || die
+
+	if ! use static-libs; then
+		find "${ED}" -type f -name "*.a" -delete || die
+	fi
+
+	dodoc README
+}